Real-Time Bioprocess Control with
smart VOC Sensors & fermHUB

VOC sensor technology for early detection of metabolic changes or stress.

fermHUB for smart monitoring and control of fermentation processes - flexible, vendor-neutral, open-source.

fermSENSE - VOC sensors as "Metabolic Stress Detection System"

Laboratory set-up for the use of the fermSENSE-CUBE in metabolic stress analysis

fermHUB for process optimization, e.g. with the "Golden Batch Autopilot"

fermHUB data graph for the "Golden Batch Autopilot"

Why VOC Sensing beats
conventional Probes

Short response time

detecting Volitile Organic Compounds is much more sensitive than measuring broad macro-gas balances

Early deviation detection

VOC sensors work as an early warning system of meabolic stress, which often leads in the production of side products

No complex calibration needed

VOC sensing focuses on real-time trend patterns rather than absolute values, eliminating expensive technology, time-consuming and error-prone calibration routines.

Advanced control potential

VOC monitoring and data processing via fermHUB enable precise, AI-supported control, rather than manual or static control strategies.

fermHUB – flexible, vendor-neutral open-source platform for smart monitoring and control of bio processes

News and Use Cases

R. ten Haaft (Bronkhorst); F. Eiden (Westphalian University of Applied Sciences, Recklinghausen)

Precise fed-batch bioreactor monitoring with Bronkhorst mass flow control and fermSYS – VOC sensors

Real-time volume tracking & metabolic stress analysis in the bioreactor: Find out how fermSYS & Bronkhorst automate fed-batch processes using plug-and-play technology.

Karin Ammon (fermSYS)

6 days ago3 min read

Nick Harbring, BSc, at Westfälische Hochschule in Recklinghausen, using fermHUB-SCADA for fermentation control

With fermHUB and ‘Golden Batch Fermentation’, I no longer find any surprises in the bioreactor

Reproducibility is the biggest challenge in fermentation. With the Golden Batch Fermentation feature in fermHUB, you can turn past successes into a clear target range for every new batch. Live data is compared in real time with the best historical runs, whilst predictive analytics identify trends at an early stage and provide specific recommendations for action – ensuring maximum yield and full process control.

N. Harbring (Westph. Univ.); K. Ammon (fermSYS)

Oct 72 min read

fermSYS Buddy - used in the production of water kefir

fermSYS VOC-Buddy for making water kefir with intelligent fermentation control

fermSYS Buddy: Dynamic Bioprocess Control for Water Kefir Discover how the fermSYS Buddy transforms water kefir fermentation from static recipes into an intelligent, automated bioprocess. By connecting the compact fermSYS CUBE to a dosing pump via ad-hoc Wi-Fi, it enables real-time feedback and PID-controlled dynamic feeding. Combining biotechnology, AI, and smart hardware optimizes substrate use, enhances taste consistency, shortens production times, and leads the way to aut

Karin Ammon (fermSYS)

Aug 312 min read

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About us

We unlock the intelligence inside your bioprocess!

Our vision is to make industrial and biotechnological processes fully transparent, predictive, and sustainable through intelligent sensing and data-driven systems.

We envision a future in which processes can be understood in real time, safely controlled, and continuously optimized—from laboratory scale to industrial production.

Our mission is to combine easy sensing with intelligent data processing to enable informed and real-time decision-making.

fermSYS offers:

flexible VOC sensors for industrial and laboratory application
a local process data platform for data management, visualization and process control (take what you have)
AI-powered and cloud-based solutions that transform process data into actionable insight.

Real-Time Bioprocess Control with smart VOC Sensors & fermHUB

Why VOC Sensing beats conventional Probes