At the Vorholt Lab (Institute of Microbiology, ETH Zurich), researchers are engineering *Escherichia coli* to efficiently utilize green methanol as a sustainable one-carbon feedstock. Using the fermSYS VOC sensor for real-time methanol monitoring, the team gains continuous process insights that accelerate strain development and optimize fermentation strategies—advancing sustainable biomanufacturing and supporting the transition to a circular carbon economy.

Media screening is no longer just about biomass, O₂ and CO₂. By combining the Kuhner TOM system with the fermSYS fermSENSE – MULTI FLOW, volatile organic compounds (VOCs) provide real-time metabolic insights, revealing by-product formation and cellular stress long before endpoint analysis. More data, better decisions, faster process development – transforming a shaker into an intelligent mini-bioreactor.

By combining fermSYS’s innovative VOC sensor technology and smart fermentation vison with Bronkhorst’s high-precision flow measurement and control equipment, we are laying the foundations for improved process control, greater efficiency and deeper insights into biological processes.

Monitoring fermentation processes is easy. With the fermSYS Cube, you get a compact, all-in-one solution for measuring, controlling and analysing data from shake flask or laboratory fermentations. The Cube combines all the necessary components in a single device – from the VOC sensor and control software to wireless communication.

Explore how 'Real-time insight into bioprocesses via VOC sensing is becoming reality.' with cutting-edge VOC sensing tech for smarter bioprocessing.